Polynucleotides
What are Polynucleotides?
Polynucleotides (PNs) are biocompatible, naturally derived DNA fragments that have powerful regenerative properties. In aesthetic medicine, they are used in injectable treatments to repair, rejuvenate, and regenerate the skin at a cellular level.
Unlike fillers, which add volume, polynucleotides work by stimulating the skin’s natural healing and repair processes, improving overall skin quality, texture, and resilience.
How Do Polynucleotides Work?
Polynucleotides act as biostimulators with multiple effects:
- Cell Regeneration → Promote repair of damaged cells and tissues
- Collagen & Elastin Stimulation → Activate fibroblasts to boost collagen and elastin production for firmer, more elastic skin
- Hydration → Attract and bind water molecules, providing deep and lasting skin hydration
- Antioxidant Action → Neutralize free radicals, reducing oxidative stress and slowing visible aging
- Healing Support → Enhance tissue recovery after injury or other skin treatments
Benefits of Polynucleotide Treatments
- Improves skin texture, tone, and elasticity
- Reduces fine lines, wrinkles, and crepey skin
- Provides deep, natural hydration and radiance
- Helps reduce acne scars, pigmentation, and sun damage
- Supports healing after aesthetic treatments (microneedling, laser, peels)
- Safe for delicate areas such as under-eyes, neck, and décolletage
Treatment Process
Polynucleotides are delivered through small injections into the skin. A course of treatments (typically 2–4 sessions spaced a few weeks apart) is recommended for best results, with improvements continuing to build over several months as collagen and elastin production is stimulated.
✨ In summary: Polynucleotides don’t just mask signs of aging—they repair and restore skin health from within, making them one of the most advanced regenerative treatments in modern aesthetics.